www.cancerwire.com
Johan
Haux, MD, PhD
Med. dr. & Överläkare
(Consultant in medical oncology)
------------------------------------------------------
Digitalis, digitoxin, digoxin,
Coley toxins, cytokines,
cancer
Digitoxin elicits anti-inflammatory and vasoprotective properties in endothelial
cells: Therapeutic implications for the treatment of atherosclerosis ?
Atherosclerosis, In Press, Accepted Manuscript, Available online 25 March 2009
Joanna Jagielska, Gustavo Salguero, Bernhard Schieffer, Udo Bavendiek
Novel therapeutic applications of cardiac glycosides. Prassas I, Diamandis EP. Nat Rev Drug Discov. 2008 Nov;7(11):926-35.
Cardiac glycosides as novel cancer therapeutic agents. Mol Interv. 2008 Feb;8(1):36-49.Newman RA, Yang P, Pawlus AD, Block KI.M. D. Anderson Cancer Center, Houston, TX
Anti-HSV activity of digitoxin and its possible mechanisms Antiviral Research, In Press, Uncorrected Proof, Available online 21 February 2008
Recruiting now: A pilot phase II study of digitoxin for Androgen-Independent Prostate Cancer (AIPC) March 2007 Principal investigator J. Haux
Digitalis for Bird Flu? 10 January 2006 J. Haux
Digitalis: The Insulin for Cancer? April 17, 2006
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization PNAS August 16, 2005
Foxgloves can fight cancer Gemini 2001
Cardiac
glycosides inhibit TNF-{alpha}/
The
dynamics of cell proliferation.
Med
Hypotheses. 2004;62(4):556-63.
Digitalis;
impinges on more than just the (ion-) pump.
Med
Hypotheses. 2002 Dec;59(6):781-2.
Digitoxin
medication and cancer; case control and internal dose-response studies.
Infection
and cancer.
Lancet.
2001 Jul 14;358(9276):155-6.
Some
information
in Norwegian and some more in Legemidler
og samfunn
Digitoxin
is a potential anticancer agent for several types of cancer.
Med
Hypotheses. 1999 Dec;53(6):543-8.
Digitoxin,
in non-toxic concentrations, inhibits proliferation and induces cell death in
prostate cancer cell lines
Haux J, Lam M, Marthinsen ABL, Strickert
T, Lundgren S.
Z Onkol 1999;31: 14-20
Haux J,
Marthinsen ABL, Gulbrandsen M, Alfredsen AS, Johansen H, Strickert.
Z Onkol 1999;31: 61-65
Regulation
of APO-2 ligand/trail expression in NK cells-involvement in NK cell-mediated
cytotoxicity.
Cytokine.
1999 Sep;11(9):664-72.
The
role of interleukin-2 in regulating the sensitivity of natural killer cells for
Fas-mediated apoptosis.
Cancer
Immunol Immunother. 1999 May-Jun;48(2-3):139-46.
Regulation
of Fas and Fas-ligand expression in NK cells by cytokines and the involvement of
Fas-ligand in NK/LAK cell-mediated cytotoxicity.
Cytokine.
1997 Jun;9(6):394-404.
Address reprint requests and correspondence to:
Johan Haux, MD, PhD jhaux@operamail.com
